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Research & Evidence

Floater-focused research. Broader daily eye nutrition.

Explore research on eye floaters, retinal carotenoids, macular pigment, and tear-film measures related to dry eye and screen use. See the evidence

Our approach

Built around floater research.
Broadened for daily eye nutrition.

Haro Clear combines five nutrient categories represented in FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. , 900 mg of fruit enzymes per daily serving, and the retinal carotenoids lutein and zeaxanthin.

Retinal carotenoids

8mg

lutein + zeaxanthin

Carotenoids found in the retina and lens, included in every daily Haro Clear serving.

Daily enzyme serving

900mg

bromelain + papain

The largest ingredients in the formula by weight.
Pineapple and papaya, the sources of bromelain and papain
Purple grapes and fresh orange halves on a warm stone surface

FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. connection

Five targeted micronutrients.

Broader eye nutrition

9

complementary ingredients

Enzymes, carotenoids and targeted micronutrients in one routine.

Eye Floater Supplement Research

What have studies on fruit enzymes and targeted nutrients found—and how do they relate to Haro Clear?

Fruit enzyme study A 2022 trial of bromelain, papain and ficin in adults with vitreous floaters. : what it tested

Two daily capsules of Haro Clear provide 600 mg bromelain and 300 mg papain. Together, these fruit-derived enzymes contribute 900 mg and are the formula’s largest ingredients by weight.

900 mgfruit enzymes per daily Haro Clear serving
224 patients studied
3months of study follow-up

Published visual evidence

Compare the study’s before-and-after figures.

Case examples reproduced from the published 2022 mixed-fruit-enzyme study.

Drag left or right to compare. Keyboard: use the arrow keys; Home and End reveal each image.

Study Figure 1 · B-scan ultrasonography
Figure 1 B-scan ultrasonography before treatment, from the published fruit enzyme study
Figure 1 B-scan ultrasonography after treatment, from the published fruit enzyme study

Before: A 55-year-old woman had one eye floater visible on a B-scan at the start of the study.

After three months: The paper reports that the floater was significantly reduced on the follow-up B-scan after she received the mixed fruit enzyme supplement tested in the study.

Study Figure 2 · Color fundus photography
Figure 2 color fundus photograph before treatment, from the published fruit enzyme study
Figure 2 color fundus photograph after treatment, from the published fruit enzyme study

Before: A 58-year-old man with diabetes had a dark-red cloud over the retina caused by bleeding inside the eye.

After three months: The paper reports that the clouding decreased and his vision improved from 20/200 to 20/40 after he received the mixed fruit enzyme supplement tested in the study.

What was tested?

The 2022 study included 160 participants with spontaneous vitreous opacities and 64 with hemorrhage-related opacities. These are different clinical situations; the before-and-after examples should be read in that context. Over three months, participants received a vitamin C comparator or one, two or three daily capsules of a combination containing bromelain, papain and ficin. The researchers reported improvements with the combination tested.

How to read the findings

Haro Clear centers its fruit-enzyme component on 600 mg bromelain and 300 mg papain, paired with targeted micronutrients, lutein and zeaxanthin in a nine-ingredient formula.

This trial tested bromelain, papain and ficin together. Haro Clear does not contain ficin and was not tested in this trial; these findings do not establish equivalent results for Haro Clear.

About our processResearch transparency

We cite the sources behind our study explanations and identify the tested ingredients, doses, populations and findings. Results apply to the formulas and people studied; they do not establish equivalent results for Haro Clear.

Disclosure: Haro Health owns and sells Haro Clear.

We review affected content when the label, source information or evidence changes. To flag an error, email hello@harohealth.com with the page link and the wording you want us to check. Please do not send private medical records.

Review status: Updated study explanations are under review. Previously recorded review: September 13, 2026.

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