Research & Evidence

Floater-focused research. Broader daily eye nutrition.

Explore research on eye floaters, retinal carotenoids, macular pigment, and tear-film measures related to dry eye and screen use. See the evidence

Our approach

Built around floater research.
Broadened for daily eye nutrition.

Haro Clear combines five nutrient categories represented in FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. , 900 mg of fruit enzymes per daily serving, and the retinal carotenoids lutein and zeaxanthin.

Retinal carotenoids

8mg

lutein + zeaxanthin

Carotenoids found in the retina and lens, included in every daily Haro Clear serving.

Daily enzyme serving

900mg

bromelain + papain

The largest ingredients in the formula by weight.
Pineapple and papaya, the sources of bromelain and papain
Purple grapes and fresh orange halves on a warm stone surface

FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. connection

Five targeted micronutrients.

Broader eye nutrition

9

complementary ingredients

Enzymes, carotenoids and targeted micronutrients in one routine.

Eye Floater Supplement Research

What have studies on fruit enzymes and targeted nutrients found—and how do they relate to Haro Clear?

The FLIES Floater Intervention Study (FLIES): a 2021 trial of a five-nutrient supplement for adults with symptomatic vitreous floaters. trial: targeted micronutrients for floater discomfort

The 2021 Floater Intervention Study (FLIES) was a double-blind, randomized, placebo-controlled trial. It assigned 61 adults with symptomatic eye floaters to VitroCap N or placebo for 6 months; 56 completed the trial. The active group reported less floater discomfort and had a reduction in measured vitreous opacity area; the placebo group showed no significant change in these measures. One measure of contrast sensitivity also improved in the active group.

Haro Clear includes the five nutrient categories represented in FLIES, alongside bromelain, papain, lutein and zeaxanthin for broader daily eye nutrition. FLIES tested VitroCap N, not Haro Clear; shared nutrient categories do not establish equivalent results.

61 participants randomized
6months of follow-up
56participants completed the trial

What was tested?

One daily capsule of VitroCap N supplied 125 mg L-lysine, 40 mg vitamin C, 26.3 mg grape seed extract, 5 mg zinc and 100 mg citrus-derived extract. The trial evaluated this combination as a whole.

How to read the findings

The results relate to the tested formula and study population. Haro Clear uses its own ingredient forms, amounts and two-capsule daily serving. Researchers assessed both reported floater discomfort and measured opacity area; not every participant contributed to every endpoint. The trial was small and conducted at one center. Its symptom questionnaire was not independently validated, and one masked investigator manually outlined the opacity images before software measured their area. The paper reports commercial funding and related interests.

  • Read the complete study Ankamah et al. (2021) · Translational Vision Science & Technology · 10(12):19 · DOI: 10.1167/tvst.10.12.19

Looking for Haro Clear vs. VitreousHealth? View the separate formula comparison →

About our processResearch transparency

We cite the sources behind our study explanations and identify the tested ingredients, doses, populations and findings. Results apply to the formulas and people studied; they do not establish equivalent results for Haro Clear.

Disclosure: Haro Health owns and sells Haro Clear.

We review affected content when the label, source information or evidence changes. To flag an error, email hello@harohealth.com with the page link and the wording you want us to check. Please do not send private medical records.

Review status: Updated study explanations are under review. Previously recorded review: September 13, 2026.

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